Age > 18

New diagnosis of DVT/PE

Alert and oriented

Hemodynamically stable

Troponin < 500

Patient meets Hestia Criteria (must answer NO to all)

Patient given first dose of anticoagulation

Patient does not meet Hestia Criteria

Abnormal vital signs or severe systemic illness

Concern for Anti-Phospholipid Syndrome (APLS) (Warfarin is the only standard of care anticoagulant for these patients, and will need admission to initiate)

• VTE in an unusual location (E.g. Arterial Beds, Splanchnic Vessels, Central Venous structures)

• History of Autoimmune Disease (particularly SLE)

• History of multiple unexplained miscarriages

• Clotting while on an Anticoagulant

Social issues (ie, unable to care for self; need for placement)

Pregnancy or lactating

Post-partum

Evidence of right heart strain (on CT or Echo, or ECG)

Troponin > 500

Medication interaction

Evidence of phlegmasia alba dolens/phlegmasia cerulea dolens

Acceptable VS, uncomplicated PE

No clinical evidence of worsening

Adequate home care/support available

Instructions/Prescription for novel oral anticoagulation

Patient can obtain PCP followup withing 3 weeks of discharge

Meets Hestia criteria for discharge

Patient does not meet Hestia criteria for discharge

Unstable vital signs

Bleeding complications

Home treatment not available

Provider discretion